Single Injection Adductor Canal Block Versus Continuous Adductor Canal Infusion for Total Knee Arthroplasty

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Total Knee Arthroplasty, Pain, Postoperative, Adductor Canal Block

In brief

Patients undergoing Primary Total Knee Arthroplasty will be randomized to receive either multimodal single injection adductor canal block with sham infusion catheter or continuous infusion of local anesthetic (control) for postoperative analgesia. Primary end point is pain scores at 30 hours post performance of block procedure.

Key facts

Study ID

NCT02991404

Run by

Wake Forest University Health Sciences

People needed

60

Starts

2017-02-17

Expected to finish

2017-11-15

Last updated by the study team

2018-04-05

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients will be eligible for inclusion in the study if they are:
• Age of 18 years old or older
• Scheduled to primary unilateral total knee arthroplasty.
• Patients must give written informed consent for anesthesia including continuous adductor canal block for postoperative analgesia prior to recruitment

You may not qualify if…

• Patients will be excluded if they have:
• A contraindication to an adductor canal block or catheter placement including, but not limited to site infection, irritation, or refusal.
• Poorly controlled diabetes (A1C >8.0)
• Allergy to medications involves in this study (opioids, bupivacaine, buprenorphine, clonidine, or dexamethasone)
• Opioid use >40 mg of oxycodone daily, long-acting opioids.

Where it is running

• Wake Forest Baptist Hospital — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

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