Cryobiopsy Versus Forceps Biopsy for Pulmonary Lesions

Stopped early · Not applicable

Conditions studied: Solitary Pulmonary Nodule, Multiple Pulmonary Nodules

In brief

Purpose: Patients with peripheral lung nodules require evaluation for lung cancer. Our aim is to assess the diagnostic yield of a new technique, transbronchial cryobiopsies, in patients at risk for lung cancer. Target population: Patients referred for bronchoscopy and lung biopsies as a part of their work up for peripheral lung lesions. Procedures: Patients enrolled will have forceps transbronchial biopsies followed by transbronchial cryobiopsies for their lung lesion during bronchoscopy.

Key facts

Study ID

NCT02983903

Run by

University of Pennsylvania

People needed

31

Starts

2016-11-01

Expected to finish

2020-03-02

Last updated by the study team

2020-03-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age >/= 18
• At least one peripheral lung lesion >8mm documented on CT scan referred for diagnostic bronchoscopy
• Subject is able to undergo informed consent

You may not qualify if…

• Coagulopathy (platelet count < 50,000, INR > 1.5) detected on blood testing done within 6 weeks of the procedural visit
• Lesion associated with a prominent vessel evident on CT scan
• Pure ground glass lesion
• Fibrotic interstitial lung abnormalities on chest CT
• Bullous emphysema in region of nodule
• Supplemental oxygen utilization at baseline
• BMI > 40
• End stage renal disease

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.