Marijuana's Impact on Alcohol Motivation and Consumption

Completed · Phase 2 · Has a placebo group

Conditions studied: Alcohol Drinking, Marijuana

In brief

This laboratory study will employ a repeated measures experimental design to examine the effect of high (7.2% THC) and moderate (3.1% THC) dose of marijuana, relative to placebo, on alcohol craving and on behavioral economic measure of alcohol demand after exposure to alcohol cues, and on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consume. The study will recruit 173 non-treatment seeking heavy episodic alcohol drinkers who smoke marijuana at least twice weekly.

Key facts

Study ID

NCT02983773

Run by

Brown University

People needed

157

Starts

2017-01-23

Expected to finish

2021-07-21

Last updated by the study team

2026-04-21

Who can join

Age: 21 and older, up to 44. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 21 to 44
• English-speaking
• marijuana smoking in past month
• report of current heavy episodic (binge) drinking
• in good physical health and weighing < 250 lbs
• zero breath alcohol at each visit

You may not qualify if…

• history of seizures
• smoking >20 tobacco cigarettes per day
• positive pregnancy test
• nursing
• positive urine toxicology screen for drugs other than cannabis
• interest to quit or receive treatment for marijuana or alcohol use
• meeting criteria for a current affective disorder (depression, or mania, panic disorder, and having psychotic symptoms as assessed by the SCID)

Where it is running

• Brown University — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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