Wide Spectrum Investigation of Stroke Outcome Disparities on Multiple Levels (WISSDOM)
Completed · Not applicable
Conditions studied: Stroke Ischemic, Minority Health
In brief
This research project will evaluate the relationship between cardiovascular risk factors, degrees of physical and mental activity prior to the stroke, brain tissue integrity, post-stroke community participation and neurological recovery after the stroke. Investigators will recruit and study healthy and post stroke participants, gaining insight into the possible mechanisms that explain why the adverse risk profile, which is more commonly present in African-Americans than non-Hispanic Whites in the stroke belt, is translated into a less favorable recovery post stroke.
Key facts
- Study ID
- NCT02982278
- Run by
- Medical University of South Carolina
- People needed
- 87
- Starts
- 2015-10-01
- Expected to finish
- 2020-06-30
- Last updated by the study team
- 2021-02-26
Who can join
Age: 40 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 40-75 years
- prestroke mRS score >2
- African American or White
- Reside in Berkeley, Charleston, Dorchester, Colleton or Georgetown Counties
- Ischemic stroke involving only one hemisphere
- Fugl Meyer score >16 at baseline or Aphasia Quotient in Western Aphasia Battery <93
- no contraindications to research MRI
You may not qualify if…
- Primary or secondary intracerebral hematoma, or subarachnoid hemorrhage, or subdural/ epidural hematoma; Prisoner; diagnoses of substance addiction (alcohol or illicit drugs)
- Bihemispheric acute ischemic strokes;
- Other concomitant neurological disorders, such as brain tumor, abscess or spinal cord disease affecting language or limb motor function;
- Documented history of dementia prior to index event;
- Patient suffered one or more recurrent stroke during the 12-month follow up period.
- Terminal illness with life expectancy ≤ 1 year
- Currently pregnant
- Brain stem strokes
Where it is running
- Medical University of South Carolina — Charleston, South Carolina, United States
Full record on ClinicalTrials.gov
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