Optimal Timing of Intercostal Nerve Blocks During Video-Assisted Thoracic Surgeries
Completed · Phase 4
Conditions studied: Video-Assisted Thoracic Surgery, Video-Assisted Thoracoscopic Surgery
In brief
Intercostal nerve block, performed under the guidance of videoscope, is a part of standard anesthesia procedures for patients receiving Video-Assisted Thoracic Surgeries. In this double-blind, prospective, multi-center, randomized, controlled clinical trial the investigators aim to compare preemptive versus post-closure intercostal injection of ropivacaine in controlling post-video-assisted thoracotomy pain.
Key facts
- Study ID
- NCT02980835
- Run by
- University at Buffalo
- People needed
- 36
- Starts
- 2016-09-28
- Expected to finish
- 2022-03-30
- Last updated by the study team
- 2022-09-22
Who can join
Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients will be eligible to enroll in this study if they:
- Have physical status within ASA class II or III
- Are between 18 and 85 years of age
- Are candidates for VATS
- Are able to complete VAS assessments
- Are competent to sign the informed consent form
You may not qualify if…
- Patients will not be enrolled in this study if they:
- Are pregnant
- Have allergy to ropivacaine or hydromorphone
- Have renal insufficiency (eGFR<60mL/min/1.73m2)
- Have hepatic insufficiency (AST, ALT, or both >60 U/L) or cirrhosis
- Have a predicted postoperative forced vital capacity (FVC) of <40%, predicted forced expiratory volume at 1s (FEV1) <40%
- Have coagulopathy (platelet count<50000, INR>2, or both)
- Have a history of opioid addiction, chronically taking opioids, currently taking high dose of opioids or currently taking opioid agonist+antagonist (e.g. Suboxone®)
- Are taking nonsteroidal anti-inflammatory drug, including aspirin, within a week prior to surgery (since the analgesic effects of NSAID drugs may become confounding factors).
Where it is running
- VA Western New York Healthcare System — Buffalo, New York, United States
Full record on ClinicalTrials.gov
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