Renal Biomarkers to Predict Recovery Following Venoarterial Extracorporeal Membrane Oxygenation

Stopped early

Conditions studied: Acute Kidney Injury

In brief

The investigators objective is to assess the utility of renal biomarkers in predicting renal recovery following institution of Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO). Tissue biomarkers of renal injury may provide a real-time indication of renal function and the likelihood of renal recovery in patients having cardiogenic shock and requiring VA-ECMO. In these patients, traditional markers of kidney function (urine output and serum Creatinine level) do not accurately represent renal function.

Key facts

Study ID

NCT02978378

Run by

Milton S. Hershey Medical Center

People needed

2

Starts

2017-05-01

Expected to finish

2018-03-23

Last updated by the study team

2024-12-10

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age more than 18 years
• refractory or advanced cardiogenic shock prior to institution of VA-ECMO

You may not qualify if…

• History of chronic kidney disease prior to cardiogenic shock, as defined by estimated glomerular filtration rate (GFR) less than 60 mL per min
• Cognitive impairment
• Pregnant women
• patient or surrogate is not fluent in English
• Long-term immunosuppression

Where it is running

• Milton S. Hershey Medical Center — Hershey, Pennsylvania, United States

Full record on ClinicalTrials.gov

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