Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD)
Completed · Phase 3 · Has a placebo group
Conditions studied: Chronic Graft Versus Host Disease
In brief
To evaluate the safety and efficacy of ibrutinib in combination with prednisone in subjects with newly diagnosed moderate to severe cGVHD.
Key facts
- Study ID
- NCT02959944
- Run by
- Pharmacyclics LLC.
- People needed
- 193
- Starts
- 2017-05-11
- Expected to finish
- 2021-07-12
- Last updated by the study team
- 2023-03-30
Who can join
Age: 12 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- LPCH Stanford /ID# 1140-1128 — Palo Alto, California, United States
- Ucsf /Id# 1140-0003 — San Francisco, California, United States
- Stanford University/Stanford Cancer Center, Pasteur Drive /ID# 1140-0400 — Stanford, California, United States
- UCHSC Anschultz Cancer Pavilion /ID# 1140-0068 — Aurora, Colorado, United States
- Children's National Medical Center /ID# 1140-1122 — Washington D.C., District of Columbia, United States
- Jackson Memorial Hospital, University of Miami /ID# 1140-0647 — Miami, Florida, United States
- Florida Hospital Cancer Institute/Adventist Health System/Sunbelt, Inc /ID# 1140-1121 — Orlando, Florida, United States
- Emory University, Winship Cancer Institute /ID# 1140-0033 — Atlanta, Georgia, United States
- Emory University/Winship Cancer Institute /ID# 1140-1179 — Atlanta, Georgia, United States
- University of Chicago /ID# 1140-0126 — Chicago, Illinois, United States
- Loyola University /ID# 1140-0713 — Maywood, Illinois, United States
- Indiana University Melvin and Bren Simon Cancer Center /ID# 1140-0010 — Indianapolis, Indiana, United States
- University of Kentucky /ID# 1140-1140 — Lexington, Kentucky, United States
- University of Louisville Hospital /ID# 1140-1131 — Louisville, Kentucky, United States
- University of Maryland /ID# 1140-0205 — Baltimore, Maryland, United States
- Massachusetts General Hospital Cancer Center /ID# 1140-0020 — Boston, Massachusetts, United States
- Boston Childrens Hospital /ID# 1140-1615 — Boston, Massachusetts, United States
- Dana-Farber Cancer Institute /ID# 1140-0349 — Boston, Massachusetts, United States
- Barbara Ann Karmanos Cancer In /ID# 1140-0130 — Detroit, Michigan, United States
- University of Minnesota /ID# 1140-0807 — Minneapolis, Minnesota, United States
- Mayo Clinic, Rochester, MN /ID# 1140-0240 — Rochester, Minnesota, United States
- Hackensack University Medical Center/ John Theurer Cancer Center /ID# 1140-0343 — Hackensack, New Jersey, United States
- Rutgers Cancer Institute of NJ /ID# 1140-0803 — New Brunswick, New Jersey, United States
- New York Presbyterian Hospital/Weill Cornell Med College /ID# 1140-0200 — New York, New York, United States
- Arizona Oncology - Scottsdale - Cancer Transplant Institute Location /ID# 1140-1120 — Scottsdale, Arizona, United States
Full record on ClinicalTrials.gov
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