The Effect of Almonds on Skin Lipids and Wrinkles

Completed · Not applicable

Conditions studied: Rhytides

In brief

Investigators hypothesize that regular consumption of almonds will augment the long chain fatty acid profile and the alpha-tocopherol levels, improve the skin barrier function, and improve the appearance of facial wrinkles in post-menopausal women.

Key facts

Study ID

NCT02954315

Run by

University of California, Davis

People needed

31

Starts

2016-10-25

Expected to finish

2018-04-30

Last updated by the study team

2018-10-17

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Postmenopausal women
• Fitzpatrick skin types 1 and 2
• Able to follow dietary intervention and attend all study visits

You may not qualify if…

• Those with a nut allergy
• Smoking:
• Current smokers
• Those that have smoked within the past year
• Former smokers with greater than a 20 pack-year history of smoking within the past 20 years will be excluded.
• Those with an autoimmune photosensitive condition or a known genetic condition with a deficiency in collagen production (such as Ehler-Danlos)
• Those that already obtain 20% of their energy intake from nut consumption
• Those with implausible reported energy intakes of <1,000 kcal/d or >3,000 kcal/d
• Individuals who are unwilling to discontinue high antioxidant supplements and daily food sources listed below, during the washout and intervention.

Where it is running

• UC Davis Department of Dermatology, Clinical Trials Unit — Sacramento, California, United States

Full record on ClinicalTrials.gov

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