The Effect of Alveolar Ridge Preservation After Tooth Extraction in the Posterior Maxilla

Status unconfirmed · Not applicable

Conditions studied: Tooth Extraction

In brief

This study is designed to assess the effects of Alveolar Ridge Preservation (ARP) after tooth extraction compared to extraction alone in the posterior maxilla. The results of this study will demonstrate if the use of ARP reduces alveolar ridge resorption at 6 months post extraction in the posterior maxilla region.

Key facts

Study ID

NCT02952209

Run by

NYU College of Dentistry

People needed

15

Starts

2016-09-27

Expected to finish

2021-12-01

Last updated by the study team

2021-03-09

Who can join

Age: 20 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects must voluntarily sign the informed consent form.
• Subjects must be male or female who are at least 20-70 years of age.
• Subjects must be able and willing to follow study procedures and instructions.
• Presence of one posterior tooth in the right maxilla and one posterior tooth in the left maxilla that require extraction (ADA tooth positions 2-4 and 13-15). The same type of tooth should be in booth side, either two molars or two premolars.
• Teeth extractions of one posterior tooth in the right maxilla and one posterior tooth in the left maxilla must be completed successfully (ADA tooth positions 2-4 and 13-15).
• If present, teeth adjacent to the teeth slated for extraction must be healthy. Healthy teeth are defined as asymptomatic teeth without periapical lesions.

You may not qualify if…

• Female subjects who are pregnant or lactating, or who intend to become pregnant during the study period following entrance into the study.
• Subjects who have failed to maintain good plaque control.
• Subjects with any systemic condition such as uncontrolled diabetes mellitus, cancer, HIV, disorders that compromise wound healing, chronic high dose steroid therapy, intravenous and oral bisphosphonate therapy, bone metabolic diseases, history of irradiation of the head and neck area, or any other immuno-suppressive therapy that would contraindicate oral surgical treatment.
• Subjects who report allergy or hypersensitivity to any of the products (collagen membrane and ABBM) used throughout the study.
• Presence of ≥3 mm of vertical loss of the buccal bone in relation to the palatal wall.
• Subjects with untreated periodontitis.
• Presence of acute dentoalveolar infections in the teeth slated for extraction.
• Subjects who are heavy smokers (defined as >10 cigarettes per day or >1 cigar per day) or chew tobacco, including within 3 months prior to enrollment.
• Subjects with conditions or circumstances, in the opinion of the investigator, which would prevent completion of study participation or interfere with analysis of study results, such as history of non- compliance or unreliability

Where it is running

• Bluestone Center for Clinical Research — New York, New York, United States

Full record on ClinicalTrials.gov

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