Does Intravenous Lactated Ringer Solution Raise Measured Serum Lactate?

Completed · Early Phase 1

Conditions studied: Hyperlactatemia

In brief

Lactated Ringer's (LR) solution bolus is commonly administered in the emergency department setting to seriously ill patients. It is also common to obtain blood samples to determine serum lactate levels to aid in the assessment of the patient's degree of illness. This study endeavors to determine if serum lactate levels are affected by LR fluid administration in healthy adult individuals as compared to those who receive Normal Saline (NS). Healthy adult volunteers will be used as subjects so that the illness of hospital patients does not confound the results.

Key facts

Study ID

NCT02950753

Run by

University Medical Center of Southern Nevada

People needed

30

Starts

2017-01-04

Expected to finish

2017-06-01

Last updated by the study team

2019-04-12

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy adult volunteers
• 18 years and older

You may not qualify if…

• Pregnancy or currently breast-feeding
• Prisoner
• History of conditions associated with fluid overload: heart, renal or hepatic failure
• Baseline serum lactate level >2.2mmol
• Baseline creatinine > 1.5 mg/dL

Where it is running

• University Medical Center of Southern Nevada — Las Vegas, Nevada, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.