Anesthesia for Pain After Ankle Fracture Surgery
Completed · Phase 4
Conditions studied: Chronic Pain, Ankle Fracture Surgery, Regional Anesthesia
In brief
This pilot study will test the hypothesis that prolonged regional peripheral nerve block will reduce development of chronic pain in patients undergoing surgery for ankle fracture compared to standard of care. Subjects will be followed for one year.
Key facts
- Study ID
- NCT02950558
- Run by
- University of Cincinnati
- People needed
- 14
- Starts
- 2018-05-29
- Expected to finish
- 2020-06-19
- Last updated by the study team
- 2021-07-02
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Referred for surgery for open reduction and internal fixation for ankle fracture
You may not qualify if…
- Unable to give informed consent in English
- Unable to complete surveys in English
- Unable to understand instructions for using pump in English
- Unavailable for followup
- Polytrauma; undergoing other surgeries or having other orthopedic injuries related to the precipitating cause of the ankle fracture
- Infection
- Peripheral vascular disease
- Diabetes
- Currently undergoing chemotherapy
- Pregnancy
- Currently lactating
- Heart disease or heart rhythm disorder or taking anti-arrhythmic drugs
- Severe renal impairment (Class 3 or worse kidney disease)
- Liver disease (cirrhosis or liver failure)
- Prior allergic reaction to any type of local anesthetic
- Taking therapeutic doses of anti-coagulants or anti-platelet therapy (prophylactic doses started because of hospital admission are not an exclusion)
- Currently taking antidepressants or other psychiatric medications
- Single shot local nerve block prior to surgery was ineffective
- Selected for neuraxial anesthesia rather than general anesthesia for the open reduction surgery
- Already receiving chronic analgesic therapy for a separate chronic pain condition
Where it is running
- University of Cincinnati Medical Center — Cincinnati, Ohio, United States
- UC Health West Chester Hosptial — West Chester, Ohio, United States
Full record on ClinicalTrials.gov
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