Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility

Recruiting now · Not applicable

Conditions studied: Endometriosis, Infertility

In brief

The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)

Key facts

Study ID

NCT02948972

Run by

University Hospital, Lille

People needed

120

Starts

2016-11-17

Expected to finish

2026-05-01

Last updated by the study team

2026-04-22

Who can join

Age: 18 and older, up to 38. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Primary and secondary infertility
• Indication for IVF
• Persistent pain related to endometriosis with analgesic medical treatment failure
• Persistent pain including at least one of the following digestive symptoms related to endometriosis: Dyschesia / Sub-occlusive syndrome / Rectal bleeding / Painful defecation
• Colorectal deep infiltrating endometriosis : Whatever lesion size / With at least rectal serosal involvement / Confirmed by MRI and 1 different investigation: vaginal ultrasound echography or coloscopic CT scan or rectal endoscope ultrasound
• Eligible for DIE surgery

You may not qualify if…

• Contraindication to pregnancy or to IVF
• Viral risk
• Previous IVF cycle(s)
• Previous colorectal surgery
• Need of myomectomy during surgery
• The use of oocytes donor

Where it is running

• CHU — Clermont-Ferrand, France (enrolling)
• Hôpital Jeanne de Flandres, CHRU — Lille, France (enrolling)
• AP-HP, Hôpital Tenon — Paris, France (enrolling)
• CHU — Poissy, France (enrolling)
• CHU — Rouen, France (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.