Neural Mechanisms for Appetitive Responses to High Reward Foods

Completed

Conditions studied: Appetitive Behavior, Obesity

In brief

This study is aimed at understanding neuroendocrine responses to different types of sugars and how this influences feeding behavior among lean, overweight, and obese individuals.

Key facts

Study ID

NCT02945475

Run by

University of Southern California

People needed

114

Starts

2016-02-01

Expected to finish

2020-03-13

Last updated by the study team

2021-04-20

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18-35 years, right-handed, weight change <2% for at least 3 months prior to participation, no history of diabetes or other significant medical problems, fasting glucose <126 mg/dl.
• Lean group: BMI of 19-24.9 kg/m2
• Obese Group: BMI 30-40 kg/m2
• Overweight Group: BMI of 25-29.9 kg/m2

You may not qualify if…

• Neurological, psychiatric or addiction disorder, fasting glucose ≥126 mg/dl, use of prescription medication (with the exception of contraceptives), tobacco use, contraindications to MRI scanning (detailed in Protection of Human Subjects), fructose intolerance, history of eating disorder, actively trying to lose weight.

Where it is running

• Alexandra Yunker — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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