Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids

Stopped early · Phase 1 · Has a placebo group

Conditions studied: Chronic Pain

In brief

The goal of this research proposal is to determine if the intraoperative administrative of Ketamine and Magnesium during laparoscopic gynecologic surgery improves postoperative pain in patients on chronic opioid therapy for management of chronic pelvic pain.

Key facts

Study ID

NCT02940509

Run by

Milton S. Hershey Medical Center

People needed

20

Starts

2017-07-01

Expected to finish

2018-02-27

Last updated by the study team

2022-05-27

Who can join

Age: 18 and older, up to 80. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Subjects undergoing elective laparoscopic gynecologic surgery
• Patients with chronic pelvic pain defined as pain that has persisted for more than 6 months in duration which is localized to the pelvis, anterior abdominal wall, lower back or buttocks and has leads to functional disability or medical care1
• Patients requiring opioids daily for >1 month
• Consenting adults age 18-80
• American Society of Anesthesiologists (ASA) Physical Status classification II to ASA III

You may not qualify if…

• Patient refusal
• Chronic Kidney disease (Creatinine>2)
• Patients treated with methadone
• Known allergy or adverse effect of ketamine or magnesium
• Patient unable to give informed consent
• Patient with limited or no English fluency
• Uncontrolled hypertension

Where it is running

• Milton S. Hershey Medical Center — Hershey, Pennsylvania, United States

Full record on ClinicalTrials.gov

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