Ocular Comfort and Inflammation in Lid Hygiene Therapy
Stopped early · Not applicable
Conditions studied: Blepharitis
In brief
The primary study objectives are: to evaluate (1) the change in ocular discomfort at 30 days and (2) the change in signs and symptoms of ocular surface disease in demodex-positive subjects beginning the use of Avenova.
Key facts
- Study ID
- NCT02938078
- Run by
- Minnesota Eye Consultants, P.A.
- People needed
- 14
- Starts
- 2016-10-01
- Expected to finish
- 2018-08-24
- Last updated by the study team
- 2020-08-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subject signed and dated a IRB-approved informed consent document
- Mild or greater Demodex (minimum 15 observable mites in six lashes)
- Score of 20 or more on the OSDI Questionnaire
- Score of 20 or more on the Eyelid Inflammation Questionnaire
You may not qualify if…
- Currently enrolled in another prospective research study
- Unable to attend two follow-up visits over 30 days
- Current allergic conjunctivitis of the cornea, conjunctiva, or eyelid in either eye
- Prior ocular trauma where surgery was indicated
- Prior corneal transplant in either eye
- Any ocular surgery within the past six months
- Abnormal corneal scarring, erosions, or Stevens-Johnson syndrome
- Anticipation of ocular surgery within the next 30 days
- Non-English speaking
- Pregnant, nursing, or expect to become pregnant within the next 30 days
- Known sensitivity to chlorine or Avenova
- Moderate, or severe conjunctivochalasis
- Contact lenses within the last 30 days and unwilling to discontinue for 30 days
- Use of topical cyclosporine for less than 6 continuous months prior to baseline
- Procedure such as pulsed light or commercial lid massage in last 30 days
- Known history of autoimmune disease
- Punctal plugs placed within the last 30 days
- Use of Avenova or other lid cleansers within the last 30 days
- Changes in systemic or ocular medications in the last 30 days
- Unwilling to commit to the same ocular and systemic medications for 30 days
Where it is running
- Minnesota eye Consultants, PA — Bloomington, Minnesota, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.