Effects of Cigar Flavors on Measures of Abuse Liability Among Young Adults

Completed · Not applicable

Conditions studied: Tobacco Products

In brief

This study involves 25 current young adult combustible tobacco cigarette (CTC) smokers who will complete 5 Latin square ordered, within-subject, laboratory conditions that differ by the tobacco product smoked: 1. own-brand CTC (positive control), 2. original-flavored Black \& Mild (B\&M) cigar, 3. apple-flavored B\&M cigar, 4. cream-flavored B\&M cigar, and 5. wine-flavored B\&M cigar.

Key facts

Study ID

NCT02937051

Run by

Virginia Commonwealth University

People needed

25

Starts

2016-10-01

Expected to finish

2019-04-12

Last updated by the study team

2019-04-23

Who can join

Age: 18 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• To be included, participants must be healthy, as determined by self-report and heart rate/blood pressure (HR/BP) check, between the ages of 18-25, and willing to provide informed consent.
• They must agree to attend the lab and abstain from tobacco/nicotine as required, to use the designated products, and to follow the study protocol.
• Participants must also be regular CTC smokers (≥5 cigarettes/day for past 3 months) naïve to cigar products (smoked no more than 10 cigar products of any type in lifetime) who can provide a semi-quantitative urine cotinine result of ≥3 at screening (NicAlert test).

You may not qualify if…

• Individuals with a self-reported history of chronic diseases or psychiatric conditions will be excluded.
• Other exclusion criteria are: history of or active cardiovascular disease, current oral health problems or injuries, low/high BP, seizures, regular prescription medication use (other than vitamins or birth control), and past month use of cocaine, opioids, benzodiazepines, and methamphetamine (self-report).
• Individuals who report using marijuana or alcohol >20 days in the past 30 or interest in quitting CTC use within the next 30 days will also be excluded.
• Women will be excluded if they are breast-feeding or test positive for pregnancy (by urinalysis) at screening.

Where it is running

• VCU Behavioral Health Research Laboratory — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

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