Early PKD Observational Cohort Study

Recruiting now

Conditions studied: Polycystic Kidney Disease

In brief

This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.

Key facts

Study ID

NCT02936791

Run by

University of Kansas Medical Center

People needed

250

Starts

2016-04-01

Expected to finish

2031-06-01

Last updated by the study team

2026-04-27

Who can join

Age: 4 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Inclusion for early stage autosomal dominant polycystic kidney disease (ADPKD):
• Family history of PKD
• All races and ethnic groups
• Glomerular filtration rate (GFR) >80 ml/min per 1.73 m2
• Inclusion for Healthy Volunteers:
• Male or female with no family history of kidney disease
• All races and ethnic groups
• Normal GFR

You may not qualify if…

• Non-insulin or insulin-dependent diabetes mellitus
• Systemic illness (i.e.systemic lupus erythematosus, vasculitis)
• Unable to provide written informed consent
• Unavailable for magnetic resonance imaging (MRI) and blood/urine collection

Where it is running

• University of Chicago — Chicago, Illinois, United States (enrolling)
• University of Kansas Medical Center — Kansas City, Kansas, United States (enrolling)
• Children's Mercy Hospital — Kansas City, Missouri, United States (enrolling)

Full record on ClinicalTrials.gov

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