Coronary Revascularization Assessed by Stress PET

Status unconfirmed

Conditions studied: Coronary Stenoses, Myocardial Ischemia, Coronary Artery Stenosis, Coronary Disease, Coronary Occlusion

In brief

Regional absolute myocardial blood flow during stress (sMBF) as measured by Positron Emission Tomography (PET) improves post mechanical revascularization provided there is a baseline stress induced perfusion defect. Coronary revascularization performed on regions without a stress induced perfusion defect does not increase the sMBF.

Key facts

Study ID

NCT02931331

Run by

Ochsner Health System

People needed

50

Starts

2016-03-01

Expected to finish

2017-12-01

Last updated by the study team

2017-10-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individuals who undergo cardiac stress PET and subsequently undergo coronary angiography and mechanical revascularization. Mechanical revascularization is defined as PCI and/or coronary artery bypass grafting (CABG).
• Adults ≥18 and able to give informed consent.

You may not qualify if…

• Individuals with acute ST-elevation myocardial infarction (< 3 days)
• Individuals where absolute flow data is not available on the initial PET stress.
• Individuals who are unable to perform PET scanning secondary to hemodynamic instability.
• Individuals who are medically noncompliant with post revascularization drug therapy.
• Women who are pregnant at the time of PET2

Where it is running

• Ochsner Medical Center — New Orleans, Louisiana, United States

Full record on ClinicalTrials.gov

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