Pentosan Polysulfate Sodium and Meclofenamic Acid as Treatments in Patients With Psychotic Disorders
Completed · Phase 2
Conditions studied: Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
In brief
This study evaluates the feasibility of administering meclofenamic acid or pentosan polysulfate sodium as an adjunctive treatment to patients diagnosed with a psychotic disorder. Half of participants will receive meclofenamic acid, while the other half will receive polysulfate sodium.
Key facts
- Study ID
- NCT02930005
- Run by
- The University of Texas Health Science Center, Houston
- People needed
- 8
- Starts
- 2015-08-07
- Expected to finish
- 2016-10-06
- Last updated by the study team
- 2019-03-26
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, bipolar I disorder, delusional disorder, other specified schizophrenia spectrum and other psychotic disorders, unspecified schizophrenia spectrum and other psychotic disorders
- Negative pregnancy test in females of childbearing age
You may not qualify if…
- Urine drug screen positive for psychostimulants such as cocaine, amphetamines and ecstasy
- Any infection, neoplasm, autoimmune disease or other primary inflammatory condition (3) Previous diagnosis of intellectual disability or dementia
- Current treatment with heparin
- Use of or allergy to non-steroidal anti-inflammatory agent or pentosan polysulfate sodium
- Current or anticipated corticosteroid use
- History of peptic ulcer disease, gastro esophageal reflux disease, or gastrointestinal bleeding
- Those on warfarin or any anticoagulant
- Current treatment with lithium or asthma medication
- Individuals with pre-existing liver, cardiac, or kidney disease
Where it is running
- The University of Texas Health Science Center at Houston — Houston, Texas, United States
Full record on ClinicalTrials.gov
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