Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation Therapy
Stopped early · Phase 3 · Has a placebo group
Conditions studied: Node Positive HER2 Negative Breast Cancer
In brief
This randomized phase III trial studies how well aspirin works in preventing the cancer from coming back (recurrence) in patients with human epidermal growth factor receptor 2 (HER2) negative breast cancer after chemotherapy, surgery, and/or radiation therapy. Aspirin is a drug that reduces pain, fever, inflammation, and blood clotting. It is also being studied in cancer prevention. Giving aspirin may reduce the rate of cancer recurrence in patients with breast cancer.
Key facts
- Study ID
- NCT02927249
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 3021
- Starts
- 2016-12-08
- Expected to finish
- 2023-02-15
- Last updated by the study team
- 2023-04-05
Who can join
Age: 18 and older, up to 69. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Southern Cancer Center PC-Daphne — Daphne, Alabama, United States
- Southern Cancer Center PC-Mobile — Mobile, Alabama, United States
- Southern Cancer Center PC-Providence — Mobile, Alabama, United States
- Southern Cancer Center PC-Springhill — Mobile, Alabama, United States
- Anchorage Associates in Radiation Medicine — Anchorage, Alaska, United States
- Anchorage Radiation Therapy Center — Anchorage, Alaska, United States
- Alaska Breast Care and Surgery LLC — Anchorage, Alaska, United States
- Alaska Oncology and Hematology LLC — Anchorage, Alaska, United States
- Alaska Women's Cancer Care — Anchorage, Alaska, United States
- Anchorage Oncology Centre — Anchorage, Alaska, United States
- Katmai Oncology Group — Anchorage, Alaska, United States
- Providence Alaska Medical Center — Anchorage, Alaska, United States
- Fairbanks Memorial Hospital — Fairbanks, Alaska, United States
- Arizona Breast Cancer Specialists-Gilbert — Gilbert, Arizona, United States
- Virginia G Piper Cancer Care-Glendale — Glendale, Arizona, United States
- Kingman Regional Medical Center — Kingman, Arizona, United States
- Arizona Center for Cancer Care-Peoria — Peoria, Arizona, United States
- Cancer Center at Saint Joseph's — Phoenix, Arizona, United States
- Arizona Breast Cancer Specialists-Phoenix — Phoenix, Arizona, United States
- Arizona Breast Cancer Specialists — Scottsdale, Arizona, United States
- Arizona Breast Cancer Specialists-Scottsdale — Scottsdale, Arizona, United States
- Virginia G Piper Cancer Care-Del Camino — Scottsdale, Arizona, United States
- Arizona Center for Cancer Care-Surprise — Surprise, Arizona, United States
- Highlands Oncology Group PA - Fayetteville — Fayetteville, Arkansas, United States
- University of Alabama at Birmingham Cancer Center — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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