A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses

Completed · Not applicable

Conditions studied: Drug Overdose, Opioid-Related Disorders, Drug Addiction, Drug Abuse, Substance Abuse

In brief

This project will further develop and test the Tailored Telephone Intervention delivered by Peers to Prevent Recurring Opioid Overdoses (TTIP-PRO), a promising, low-cost, intervention to facilitate entry into medication assisted treatment (MAT) for individuals experiencing a non-fatal opioid overdoses (OOD). A prior small-scale pilot/feasibility study of TTIP-PRO (NCT02282306) found that the participating patients and the Peer Interventionists were satisfied with their participation, the intervention was acceptable, and the system for generating patient-tailored intervention information performed well. The overall goal of the present study is to conduct a pilot randomized controlled trial of TTIP-PRO versus a control group. It is hypothesized that patients in the TTIP-PRO group will have more favorable drug-abuse-related outcomes than patients in the control group.

Key facts

Study ID

NCT02922959

Run by

University of Cincinnati

People needed

80

Starts

2017-02-07

Expected to finish

2019-07-25

Last updated by the study team

2020-06-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Report having been treated for an OOD within the past 6 months
• Age 18 years or older;
• Scores "high risk" for heroin and/or non-medical use of prescription opioids on the National Institute on Drug Abuse modified Alcohol, Smoking and Substance Involvement Screening Test (NIDA-modified ASSIST) (i.e., ≥ 27)
• Be able to understand the study, and having understood, provide written informed consent in English
• Access to a phone (for TTIP-PRO intervention and phone follow-up)
• Be willing to have their intervention audio recorded and rated if randomized to TTIP-PRO
• Have an opioid-positive baseline/screening urine drug screen.

You may not qualify if…

• In the judgment of the investigator, would not be expected to complete the study protocol (e.g., due to relocation from the clinic area, probable incarceration, etc.)
• Current engagement in addiction treatment
• Residence more than 40 miles from the location of follow-up visits
• Inability to provide sufficient contact information (must provide at least 2 reliable locators)
• Prior participation in the current study.

Where it is running

• University of Cincinnati Addiction Sciences Division — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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