Anesthetics to Prevent Lung Injury in Cardiac Surgery

Completed · Phase 1/Phase 2

Conditions studied: Inflammatory Lung Injury, Ischemia-Reperfusion Lung Injury, Postoperative Pulmonary Complications

In brief

The purpose of this study is to investigate whether the use of inhaled anesthetics, compared to intravenous anesthetics, can affect the amount of lung inflammation and postoperative respiratory complications seen after cardiac surgery.

Key facts

Study ID

NCT02918877

Run by

Beth Israel Deaconess Medical Center

People needed

51

Starts

2017-06-09

Expected to finish

2021-02-01

Last updated by the study team

2021-05-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (age 18+)
• Undergoing cardiac surgery with cardiopulmonary bypass

You may not qualify if…

• Emergency surgery
• History of severe COPD, emphysema, or ILD
• Recent (<2wk) or current use of systemic glucocorticoids
• Prior history of pneumothorax
• Allergy/contraindication to intravenous anesthetics
• Personal or family history of malignant hyperthermia or high risk for malignant hyperthermia

Where it is running

• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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