Intravenous Sub-dissociative Dose Ketamine Injection Versus Infusion for Analgesia in the Emergency Department

Completed · Phase 4 · Has a placebo group

Conditions studied: Pain

In brief

Objective: The purpose of this study is to determine if administering ketamine as an intravenous (IV) infusion over 15 minutes, as compared to an IV push, will decrease adverse drug reactions without attenuating its analgesic effects. Study design: prospective, randomized, controlled, double-blind trial.

Key facts

Study ID

NCT02916927

Run by

Alameda Health System

People needed

62

Starts

2016-09-01

Expected to finish

2017-04-01

Last updated by the study team

2020-04-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Pain NRS ≥5
• Anticipated stay in ED ≥1 hour

You may not qualify if…

• Pregnant or breast feeding
• Vital sign abnormalities (SBP <90, SBP > 180, HR < 50, HR > 150, RR <10, RR > 30, weight <45 kg, weight > 115 kg)
• Arrhythmias
• Altered mental status (active psychosis/delirium)
• Administration of opioid pain medication in previous 1 hour
• history of acute head or ocular trauma
• presence of known intracranial mass or vascular lesion

Where it is running

• Alameda Health System, Highland Hospital — Oakland, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.