Intravenous Lidocaine Versus Morphine for Severe Pain in the ED

Completed · Phase 4

Conditions studied: Pain

In brief

Objective: Evaluate the analgesic efficacy of intravenous (IV) lidocaine versus provider chosen dose of IV morphine for the treatment of severe pain in the emergency department. Study design: Open-label, randomized controlled pilot study.

Key facts

Study ID

NCT02912195

Run by

Alameda Health System

People needed

32

Starts

2016-03-01

Expected to finish

2016-09-01

Last updated by the study team

2020-04-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subject has severe pain (NRS ≥7)
• Subject has anticipated ED stay of ≥1 hour

You may not qualify if…

• High acuity trauma patients
• Patients deemed to critically ill by ED provider
• Active psychosis
• Pregnancy
• History of heart block or bradycardia
• Allergy to lidocaine or amide type local anesthetic
• History of seizures

Where it is running

• Alameda Health System, Highland Hospital — Oakland, California, United States

Full record on ClinicalTrials.gov

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