Quality of Recovery After Reversal With Neostigmine or Sugammadex.

Completed · Phase 4

Conditions studied: Incomplete Reversal of Neuromuscular Block

In brief

This study will compare patient recovery measures after reversal of neuromuscular blockade with neostigmine or sugammadex after surgery. Measures include pulmonary function, muscle strength, time to extubation and quality of recovery in the post anesthesia care unit.

Key facts

Study ID

NCT02909439

Run by

Stony Brook University

People needed

80

Starts

2016-11-01

Expected to finish

2018-02-01

Last updated by the study team

2020-05-22

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participant must be willing and able to provide written informed consent for the study
• Participant must be greater than or equal to 18 years of age
• Participant must be ASA (American Society of Anesthesiologists) class I, II or III
• Planned use of neuromuscular blocking drugs
• Planned use of endotracheal intubation
• Planned for extubation to occur in the OR

You may not qualify if…

• ASA (American Society of Anesthesiologists) Class IV
• Age < 18 years old
• Inability to give oral or written consent
• Known or suspected neuromuscular disorder impairing neuromuscular function
• True allergy to muscle relaxants
• A (family) history of malignant hyperthermia
• A contraindication for neostigmine or sugammadex administration
• Serum creatinine level of greater than 2.0 mg/dL
• Surgery where the patient's arm is not available for neuromuscular monitoring
• A plan to extubate under deep anesthesia
• Pregnant

Where it is running

• Stony Brook University Hospital — Stony Brook, New York, United States

Full record on ClinicalTrials.gov

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