ROCOCO - Adaptive IMRT Versus IMPT in Head and Neck Cancer

Withdrawn before enrolling

Conditions studied: Head and Neck Neoplasms

In brief

Given the lack of evidence for the benefit of particle therapy in relevant cases, he investigators proposed an in silico trial to investigate the dosimetric effect of contour changes for OAR as well as tumor during chemoradiation in H\&N patients. Photon and proton-therapy will be compared based on dosimetric data on 7 time points during treatment combined with plan robustness. In that way the investigators will be able to assess and compare the optimal timing for replanning for photon and proton therapy. A database of the University of Pennsylvania (Upenn) consists of 10 patients with head and neck tumors treated with chemo-radiation. Contrast-enhanced CT scans were acquired prior and during RT (T1-T7)

Key facts

Study ID

NCT02908386

Run by

Maastricht Radiation Oncology

People needed

0

Starts

2015-11-01

Expected to finish

2016-11-01

Last updated by the study team

2016-09-21

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• patients with head and neck carcinoma who have been treated with radical intent 10 patients, all with a reference CT scan and CT scans at 7 time points during treatment.

You may not qualify if…

• patients with no head and neck cancer

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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