Taste Physiology in Obese Volunteers Before and After Bariatric Surgery

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Obesity

In brief

The objective is to investigate neuro-anatomical correlates of gastrointestinal taste stimulation by means of functional MRI before and after bariatric surgery. Intragastric administration of glucose, monosodium glutamate, chloroquine and placebo is followed by functional brain MRI in obese humans before and 3 months after surgery.

Key facts

Study ID

NCT02902198

Run by

University Hospital, Basel, Switzerland

People needed

16

Starts

2014-12-01

Expected to finish

2027-12-01

Last updated by the study team

2025-04-03

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• morbidly obese patients (BMI min 35kg/m2) scheduled for bariatric surgery
• right handed

You may not qualify if…

• cardiovascular disease
• neurologic/psychiatric disorders

Where it is running

• University Hopital Basel — Basel, Switzerland (enrolling)

Full record on ClinicalTrials.gov

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