NSAID Use in Postpartum Hypertensive Women

Stopped early · Phase 4

Conditions studied: Hypertension

In brief

Women who have the diagnosis of hypertension (pre-pregnancy and pregnancy induced) and deliver an infant via vaginal delivery will be placed into two groups in the postpartum period. One group will receive Ibuprofen for pain control and the other group will be given Tylenol. Blood pressures during the postpartum period will then be collected and compared in order to see if NSAIDs use increases blood pressure.

Key facts

Study ID

NCT02902172

Run by

St. Louis University

People needed

36

Starts

2017-03-15

Expected to finish

2017-10-08

Last updated by the study team

2018-10-31

Who can join

Age: 14 and older, up to 50. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• vaginal delivery
• diagnosis of chronic hypertension, chronic hypertension with superimposed preeclampsia
• preeclampsia without severe features
• preeclampsia with severe features gestational hypertension without severe range blood pressures
• gestational hypertension with severe range blood pressures
• singleton pregnancies

You may not qualify if…

• Cesarean Delivery
• no diagnosis of hypertensive disorder
• chronic or acute renal disease
• allergy to ibuprofen or acetaminophen
• lupus
• multiple order pregnancies (twins, triplets)
• Narcotic addiction/ in treatment for substance abuse/ current prescription drug user/ current use of illegal drugs

Where it is running

• St. Mary's Health Center — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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