Sleep Dysfunction and Neurocognitive Outcomes in Adolescent ADHD

Completed

Conditions studied: Attention Deficit Hyperactivity Disorder

In brief

This study seeks to characterize sleep physiology in adolescents with and without Attention deficit hyperactivity disorder (ADHD) and its relationship to differential neurocognitive and clinical outcomes within these groups.

Key facts

Study ID

NCT02897362

Run by

Duke University

People needed

62

Starts

2016-08-01

Expected to finish

2021-07-01

Last updated by the study team

2021-07-14

Who can join

Age: 13 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or Female
• Between the ages of 13-17 years, inclusive;
• Free from significant medical/psychiatric conditions
• Cognitive functioning > 80 as assessed by the KBIT-II
• Willingness to comply with all study requirements; and
• Ability of child and parent/guardian to communicate verbally and in written form in English.
• Inclusion for the ADHD group only:
• Confirmed diagnosis of ADHD, any subtype as determined by the MINI-KID
• Willingness to delay/suspend medication use for the 4-day duration of the study and 2 days prior to the sleep study phase.

You may not qualify if…

• History of chronic/significant medical condition
• Use of prescription medications for ADHD during the 2-day washout and/or 4-day study
• Current prescribed use of any other psychotropics, including non-stimulant medications for ADHD
• Current substance abuse or dependence or history within the last 6 months
• Estimated IQ < 80 as assessed by the KBIT-II
• First degree relative with psychosis or bipolar disorder;
• Parent/Guardian or child unable to communicate verbally and in written form in English; and
• Unable to comply with study requirements or otherwise unsuitable for participation in the opinion of the principal investigator
• Exclusion for the ADHD group only:
• Meets criteria for any other Axis I Disorder (determined by the MINI-KID) besides ADHD or Oppositional Defiant Disorder (ODD)
• Exclusion for the HEALTHY CONTROL group only:
• Meets criteria for any Axis I Disorder

Where it is running

• Duke Child and Family Study Center — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.