Effects of Fluid Milk in Attenuating Hyperglycemia and Hypertriglyceridemia After Meal
Completed · Not applicable
Conditions studied: Oral Glucose Tolerance Test, High Fat Tolerance Test
In brief
Epidemiological studies indicate that risk of type 2 diabetes is lower when milk is consumed in the regular diet. Milk products are unique in that they produce high insulin response despite their low glycemic index. The general aim of the proposed study is to determine the effect of fluid milk on attenuating the postprandial surge in plasma glucose and triglyceride after meals and its associated physiological mechanisms. The investigators hypothesize that the consumption of one or two servings of non-fat milk added to a standard oral glucose tolerance test (OGTT) solution or the high fat tolerance test meal will attenuate postprandial hyperglycemia and triglyceridemia. The investigators hypothesize that the postulated improvement in postprandial metabolic response due to the consumption of fluid milk will be associated with increased postprandial insulin secretion as well as insulin-mediated endothelial vasodilation and whole-limb perfusion.
Key facts
- Study ID
- NCT02894112
- Run by
- University of Texas at Austin
- People needed
- 30
- Starts
- 2013-04-01
- Expected to finish
- 2015-12-01
- Last updated by the study team
- 2016-09-09
Who can join
Age: 20 and older, up to 40. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Apparently health, sedentary. All subjects will have a BMI of 25-35 kg/m2.
You may not qualify if…
- Candidates who are taking cardiovascular-acting drugs will not be eligible for participation. Subjects with significant intima-media thickening, plaque formation, characteristics of atherosclerosis, metabolic diseases, gastrointestinal disorders, and/or renal disease will be excluded from the study. Additional exclusion criteria will be cow milk allergy or lactose intolerance, pregnancy or lactation, and alcohol abuse.
Where it is running
- Cardiovascular Aging Research Laboratory — Austin, Texas, United States
Full record on ClinicalTrials.gov
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