A Randomised Trial of Chemotherapy Plus Surgery for Recurrent Non-Small Cell Lung Cancer

Recruiting now · Phase 1 · Has a placebo group

Conditions studied: Recurrent Non-small Cell Lung Cancer

In brief

The purpose of this study is to determine if the commonly administered chemotherapeutic agents including cisplatin, carboplatin, oxaliplatin, docetaxel and gemcitabine for solid tumors in clinical oncology, either a single format or given as combinations followed by surgery are effective in the treatment of relapsed and refractory non-small cell lung cancer patients.

Key facts

Study ID

NCT02889666

Run by

Shanghai Jiao Tong University School of Medicine

People needed

500

Starts

2008-01-01

Expected to finish

2027-12-01

Last updated by the study team

2024-04-17

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≤ 75 years with histologically proven NSCLC
• No severe major organ dysfunction
• WHO performance status of 0 or 1
• No prior cancer chemotherapy
• A Clinical Stage ≥ IA (T1a, N0, M0) of lung disease but without diagnosed distant metastasis (according to the 1997 revision of the International Union Against Cancer TNM staging system) as determined by a preoperative evaluation that included a pleural computed tomography (CT) scan.

You may not qualify if…

• Age ≥ 76
• Severe major organ dysfunction
• WHO performance status of >1
• Prior cancer chemotherapy
• Stage IV

Where it is running

• China-Japan Union Hospital, Jilin University — Changchun, Jilin, China (enrolling)
• Shanghai 10th People's Hospital — Shanghai, China (enrolling)
• Shanghai Pulmonary Hospital, Tongji University School of Medicine — Shanghai, China (enrolling)

Full record on ClinicalTrials.gov

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