Nerve Burial for Preventing Neuralgia After Total Knee Arthroplasty
Stopped early · Not applicable
Conditions studied: Neuralgia, Osteoarthritis of the Knee
In brief
This is a randomized study investigating whether identification, ligation, and burial of superficial branches of the saphenous nerve crossing the surgical field during total knee arthroplasty reduces the rate of post-operative anterior knee pain and neuralgia compared to standard total knee arthroplasty.
Key facts
- Study ID
- NCT02885467
- Run by
- Medstar Health Research Institute
- People needed
- 58
- Starts
- 2013-08-01
- Expected to finish
- 2018-05-01
- Last updated by the study team
- 2018-05-21
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Must have symptomatic knee osteoarthritis under consideration for total knee arthroplasty
- Must be willing to undergo randomization
You may not qualify if…
- Age <18 or >80 years
- Known pre-operative diagnosis of neuralgia, complex regional pain syndrome, or neuropathy, about the operative lower extremity
- Known pre-operative psychiatric disorder requiring medication
- Previous surgery about the operative knee
- BMI > 40 kg/m2 (potential increased risk of soft tissue dissection through adipose)
- Ongoing pre-operative narcotic use in excess of 20 mg morphine equivalents per day for at least one month or pre-operative intravenous drug use (increased potential for complex regional pain syndrome and neuralgia, increased likelihood to require greater post-operative analgesia)
- Ongoing pre-operative use of neuropathic pain medications (gabapentin, pregabalin, amitriptyline, etc.)
- Medical comorbidities (American Society of Anesthesiologists grade > 3 or deemed unfit by consulting internist) precluding elective TKA
- Significant language barrier (reading comprehension less than 8th grade reading level) or mental condition precluding accurate self-assessment of knee pain or function.
- Severe medication allergies to permissible post-operative analgesics (acetaminophen, tramadol, oxycodone, oxycontin, dilaudid)
Where it is running
- Medstar Union Memorial Hospital — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.