Measurement of Hemodynamic Variables Under Spinal Anesthesia With Varied Positioning
Completed · Not applicable
Conditions studied: Pregnancy, Anesthesia
In brief
Multiple studies have compared spinal anesthetic performed supine versus lateral, with varying results, in parturients having elective cesarean section. Needle positioning during spinal placement has also been examined. No positioning techniques have demonstrated definitive superiority for hemodynamic stability. Investigators propose that following spinal placement in the sitting position if the patient is placed in a lateral position for 90 seconds prior to turning them supine, hemodynamic changes caused by sympathectomy related to the subarachnoid block can be avoided. This is the first study to examining the influence of position changes after spinal anesthetic placement in the sitting position, which includes hemodynamic variables not previously studied including cardiac output, TPR (total peripheral resistance) and pulse pressure variation (PPV).
Key facts
- Study ID
- NCT02883075
- Run by
- The University of Texas Medical Branch, Galveston
- People needed
- 61
- Starts
- 2017-08-01
- Expected to finish
- 2018-11-26
- Last updated by the study team
- 2019-02-28
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Parturients undergoing elective cesarean section under spinal anesthesia
- Singleton intrauterine pregnancy with appropriate gestational age fetus (AGA) at gestational age 37 to 42 weeks
You may not qualify if…
- Large for gestational age, small for gestational age, and multiple gestations
- Patients with cardiovascular disease like hypertension, etc.
- Non-English or non-Spanish speakers
- BMI >40
- Inadequate or failed blocks and inadvertently high levels of spinal blockade will be dropped from the study
- Incarcerated parturients
- Expected heavy bleeding (placenta accreta, vascular anomaly, etc.)
Where it is running
- UTMB — Galveston, Texas, United States
Full record on ClinicalTrials.gov
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