The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis

Completed · Not applicable

Conditions studied: Perforated Appendicitis

In brief

The objective of this study is to evaluate two standard post-operative pain regimens routinely used after laparoscopic appendectomy for perforated appendicitis. The investigators hypothesize that the use of intravenous (IV) acetaminophen in addition to IV ketorolac with narcotic pain pump will decrease time to transition off patient/nurse controlled analgesia (PCA) to oral pain medications.

Key facts

Study ID

NCT02881996

Run by

Children's Mercy Hospital Kansas City

People needed

90

Starts

2014-06-01

Expected to finish

2016-08-01

Last updated by the study team

2021-01-12

Who can join

Age: 2 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All patients ages 2-17 years old undergoing laparoscopic appendectomy at CMH found to have perforated appendicitis.

You may not qualify if…

• Non-perforated appendicitis
• Normal appendix at the time of operation or other associated conditions causing abdominal pain
• Patients with history of chronic pain
• Known underlying liver disorders
• Known allergy to pain medication in protocol
• Non-English speaking

Where it is running

• Children's Mercy Hospital — Kansas City, Missouri, United States

Full record on ClinicalTrials.gov

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