Oxytocin HIV Meth Study
Completed · Phase 1 · Has a placebo group
Conditions studied: Amphetamine Use Disorders
In brief
The purpose of this pilot study is to determine the tolerability, feasibility, and preliminary effectiveness of intranasal oxytocin administration prior to motivational enhancement group therapy sessions on laboratory-based measures of addiction, social connectedness, and stress responsivity in methamphetamine(meth)-using men who have sex with men (MSM). The investigators propose a randomized, double-blind, study of intranasal oxytocin versus placebo 40 IU prior to each of six Motivational Interviewing Group Therapy (MIGT) sessions in 28 mixed HIV sero-status MSM initiating treatment for amphetamine use disorder.
Key facts
- Study ID
- NCT02881177
- Run by
- University of California, San Francisco
- People needed
- 48
- Starts
- 2017-01-01
- Expected to finish
- 2018-07-01
- Last updated by the study team
- 2019-03-05
Who can join
Age: 18 and older, up to 65. Sex: male. Healthy volunteers: not accepted.
You may qualify if…
- One documented urine toxicology screen positive for meth in the past month
- Considering initiating treatment for Methamphetamine Use Disorder or initiated treatment within the past month
- History of sexual contact with men.
You may not qualify if…
- Urine toxicology screen positive for heroin in the past month
- Meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) criteria for current psychotic disorder, severe neuropsychological disorder, current moderate-severe alcohol use disorder, or suicidal or homicidal ideation with intent within the past 90-days
- Hemodialysis or inability to produce urine samples
- Sensitivity to: E 216, E 218, and chlorobutanol hemihydrate (preservatives used in nasal spray)
- Nasal Obstruction or discharge
- Using Hormone supplementation
Where it is running
- University of California, San Francisco — San Francisco, California, United States
Full record on ClinicalTrials.gov
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