Development of Attention Bias Modification for Depression
Completed · Not applicable
Conditions studied: Depression
In brief
Although negatively biased attention has a central theoretical and empirical role in the maintenance of depression, there are few behavioral treatments that successfully target and improve this deficit. The current proposal builds upon prior work and aims to further develop an attention bias modification intervention. The investigators propose to develop a highly specific intervention that directly targets negative attention bias and the neurobiology that supports it, using cutting-edge cognitive neuroscience to inform treatment development and improve quality of life of patients whose psychopathology is maintained by negative attention bias.
Key facts
- Study ID
- NCT02880215
- Run by
- University of Texas at Austin
- People needed
- 145
- Starts
- 2017-09-01
- Expected to finish
- 2019-09-26
- Last updated by the study team
- 2019-10-16
Who can join
Age: 18 and older, up to 40. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- able and willing to provide informed consent;
- fluent in English;
- moderate or greater depression symptoms;
- attention bias for negative stimuli;
- stable psychiatric and neurological medication usage.
You may not qualify if…
- meets criteria for current substance use disorder (mild or greater severity), current or past psychotic disorder, bipolar disorder, or schizophrenia;
- has any medical or physical conditions that would preclude participation in an fMRI study (e.g., orthodontic braces);
- is currently receiving psychotherapy or electroconvulsive therapy (ECT);
- current opioid analgesics or systemic corticosteroid use for an acute medical condition or taken as needed;
- has had suicidal behaviors or significant suicidal ideation within the last six months.
Where it is running
- Mood Disorders Laboratory — Austin, Texas, United States
Full record on ClinicalTrials.gov
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