Screening in Oculopharyngeal Muscular Dystrophy

Completed

Conditions studied: Oculopharyngeal Muscular Dystrophy

In brief

Oculopharyngeal muscular dystrophy (OPMD) is a rare myopathic disease that results in progressive degeneration of the oral and pharyngeal muscular, resulting in severe dysphagia and dysarthria. OPMD is considered a rare disease; therefore, limited research is available on the natural progression of the disease or the utility of biomarkers to identify swallowing impairment. The aim of this study is: 1. To identify accurate, reliable and non-invasive clinical markers of swallowing impairment 2. To determine the discriminate ability of these markers to identify impairments in swallow safety and swallowing efficiency.

Key facts

Study ID

NCT02877784

Run by

University of Florida

People needed

8

Starts

2016-10-01

Expected to finish

2017-08-01

Last updated by the study team

2020-03-27

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• diagnosis of oculopharyngeal muscular dystrophy
• no allergies to barium or capsaicin,
• no tracheotomy or mechanical ventilation
• no significant concurrent respiratory disease (e.g., COPD).

You may not qualify if…

• Pregnant Women

Where it is running

• University of Florida — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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