High Dose Vitamin D Replacement in Patients Undergoing Hematopoietic Stem Cell Transplantation

Stopped early · Not applicable

Conditions studied: Vitamin D Deficiency

In brief

The purpose of this study is to test the efficacy and safety of high dose vitamin D therapy among HSCT patients in a tiered, step-wise manner (step one/two) in order to define treatment doses capable of providing vitamin D sufficiency.

Key facts

Study ID

NCT02876822

Run by

Children's Hospital Medical Center, Cincinnati

People needed

10

Starts

2016-08-26

Expected to finish

2017-05-01

Last updated by the study team

2020-08-20

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Step 1: Patients who are preparing for HSCT, 25OHD level (<50 ng/mL), and no prior history of HSCT.
• Step 2: Patients who are preparing for HSCT 25OHD level (<50 ng/mL).
• Exclusion Criteria (both Step 1 and Step 2):
• Patients with history of pathologic fractures,
• uncorrected hypocalcemia or hypophosphatemia,
• known history of nephrocalcinosis or nephrolithiasis,
• current granulomatous disease,
• those currently in ICU.

Where it is running

• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.