TMS as a Biological Marker of Neuroplasticity

Completed

Conditions studied: Stroke, Aphasia

In brief

TMS is a non-invasive brain stimulation technique, which can be used to change the activity of a person's brain cells without needles or surgery. In this study, the invesigators are interested in the brain's ability to adapt (also called "neuroplasticity") and regain language functioning after a stroke-specifically, they want to determine whether how a person's brain responds to TMS in the short term can be used to predict how well they will recover language abilities in the long term.

Key facts

Study ID

NCT02867670

Run by

University of Pennsylvania

People needed

41

Starts

2013-07-01

Expected to finish

2020-06-01

Last updated by the study team

2020-07-08

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Must have Aphasia due to stroke
• Stroke must have occurred at least 6 months ago
• Native English speaker
• Willing \& able to have a MRI

You may not qualify if…

• Disorders of the brain other than stroke (i.e. tumor, Parkinsons, cancer... etc.)
• History of seizures/ or epilepsy
• Pacemaker or other implanted electronic devices
• Consumption of medications that lower seizure threshold
• History of psychiatric disorders
• History of tinnitus
• Current abuse of drugs or alcohol
• Pregnant or plan to get pregnant

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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