A Study Evaluating the Effects of Topical Clitoral Estradiol Cream in Post Menopausal Women

Completed · Not applicable · Has a placebo group

Conditions studied: Hypoactive Sexual Desire Disorder

In brief

The purpose of this research study is to learn about sexual function in postmenopausal women and to determine whether the use of topical clitoral application of estradiol improves women's libido, arousal, and orgasmic ability.

Key facts

Study ID

NCT02859285

Run by

ProHealth Care, Inc

People needed

30

Starts

2016-04-01

Expected to finish

2020-03-10

Last updated by the study team

2020-03-13

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Sexually active postmenopausal women of any age with complaint of vulvar and/or vaginal atrophy who also complain of bothersome decreased libido, and/or arousal, and/or orgasmic dysfunction

You may not qualify if…

• Not sexually active with a partner or an arousal device
• Uncontrolled diabetes as defined by having a consistent blood sugar level of over 100 mg/dL
• Uncontrolled hypertension as defined by an average systolic blood pressure ≥140 mmHg or an average diastolic blood pressure ≥90 mmHg, among those with hypertension
• Allergic to estradiol
• Contraindications to estradiol such as undiagnosed abnormal genital bleeding; known/suspected or history of breast cancer; known/suspected estrogen-dependent neoplasm; active deep vein thrombosis, pulmonary embolism; active or recent stroke or myocardial infarction; liver dysfunction or disease
• Spanish speaking

Where it is running

• Waukesa Memorial Hospital — Waukesha, Wisconsin, United States

Full record on ClinicalTrials.gov

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