Comparison of High Flow Nasal Cannula Therapy to Nasal Oxygen as a Treatment for Obstructive Sleep Apnea in Infants

Completed · Not applicable

Conditions studied: Obstructive Sleep Apnea

In brief

This is a small pilot study that will compare High Flow Nasal Cannula (HFNC) therapy to oxygen nasal cannula therapy on infants who have obstructive sleep apnea (OSA) and are scheduled for a clinically ordered sleep study called polysomnography (PSG). The HFNC procedure uses humidified room air delivered by nasal cannula at higher pressures and will test if HFNC can control OSA in infants better or as well as low flow nasal oxygen, the current clinical standard of care. All the infants in the study will have a brief test period of about 3 to 4 hours with the HFNC before participants begin their standard clinical PSG for titration of oxygen by nasal cannula for treatment of OSA.

Key facts

Study ID

NCT02858154

Run by

Children's Hospital Medical Center, Cincinnati

People needed

9

Starts

2016-02-01

Expected to finish

2021-07-26

Last updated by the study team

2022-03-15

Who can join

Age: 0 and older, up to 1. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Infants ≤ 12 months
• Diagnosis of OSA from previous PSG

You may not qualify if…

• Infants who on previous PSG had central apneas > 50% of the AHI

Where it is running

• Children's Mercy Hospital — Kansas City, Kansas, United States
• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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