Geniculate Artery Embolization for the Treatment of Knee Pain

Completed · Not applicable

Conditions studied: Osteoarthritis Of Knee

In brief

This study is to test a new treatment method, geniculate artery embolization (GAE), to reduce the severity of pain and disability caused by knee osteoarthritis.

Key facts

Study ID

NCT02850068

Run by

University of North Carolina, Chapel Hill

People needed

20

Starts

2017-01-25

Expected to finish

2018-08-03

Last updated by the study team

2019-08-20

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Moderate to severe knee pain (visual analog scale (VAS) > 50 mm), and
• Pain refractory to at least 3 months* of conservative therapies (anti-inflammatory drugs, or physical therapy, or muscle strengthening, or intra-articular injections), and
• Kellgren-Lawrence grade 1, 2 or 3 on radiograph of the knee.

You may not qualify if…

• Current local infection, or
• Life expectancy less than 6 months, or
• Known advanced atherosclerosis, or
• Rheumatoid or infectious arthritis, or
• Prior knee surgery, or
• Uncorrectable coagulopathy including international normalized ratio (INR) > 2.5 or platelets < 30,000, or
• Iodine allergy resulting in anaphylaxis, or
• Renal dysfunction as defined by serum creatinine >1.6 dl/mg obtained within the past 30 days.

Where it is running

• UNC Hospitals — Chapel Hill, North Carolina, United States
• Vascular Institute of Virginia — Woodbridge, Virginia, United States

Full record on ClinicalTrials.gov

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