The TREND Study: Tapered Reduction in Energy Intake as a Novel Approach to Dieting

Completed · Not applicable

Conditions studied: Obesity

In brief

TREND is a pilot randomized trial comparing two alternative methods of initiating a low-calorie weight loss diet. The study will compare the traditional diet initiation of abruptly dropping energy intake to 1000 kcal/day for women and 1200 kcal/day for men versus a 6 week tapering of energy intake from a baseline level. These two approaches will be compared with respect to their impact on energy regulatory systems of the body, weight loss and other measures, up to a year after diet initiation.

Key facts

Study ID: NCT02837211
Run by: Wake Forest University Health Sciences
People needed: 22
Starts: 2016-08-01
Expected to finish: 2018-05-11
Last updated by the study team: 2018-08-21

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Employee of Wake Forest Baptist Medical Center
BMI 30-40 kg/m2
Interested in weight loss
<90 min/wk of exercise at baseline
Receives medical care through Wake Forest and has WakeOne account

You may not qualify if…

Already participating in another diet or weight loss program or research study
History of bariatric surgery
History of eating disorder
History of cancer (other than non-melanomatous skin cancer)
History of thyroid disease
History of severe mental illness
Diagnosis of diabetes
Currently pregnant, breastfeeding or planning pregnancy
Peri or post-menopausal
Food allergies or sensitivities
Vegetarian
Night Shift worker
Planning prolonged travel in next 6-8 months or frequent out of town travel
on any medication that could promote weight loss or weight gain

Where it is running

Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

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