TMS for the Investigation of Brain Plasticity in Autism Spectrum Disorders

Completed

Conditions studied: Autism Spectrum Disorder, Intellectual Disability

In brief

The main purpose is to study brain plasticity (the changes that occur in the brain through experience) in individuals with autism spectrum disorder (ASD). Research suggests that during development, the brains of individuals with ASD may change in response to their experiences differently than the brains of typically developing individuals. Investigators want to understand why and how this difference may contribute to the symptoms of ASD.

Key facts

Study ID

NCT02836405

Run by

Boston Children's Hospital

People needed

164

Starts

2015-05-01

Expected to finish

2020-07-01

Last updated by the study team

2020-12-04

Who can join

Age: 6 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• Intracranial pathology, cerebral palsy, history of severe head injury, significant dysmorphology, or known intracranial lesion.
• History of fainting spells of unknown or undetermined etiology.
• History of head injury resulting in prolonged loss of consciousness.
• History of seizures, diagnosis of epilepsy, or immediate family history of epilepsy.
• Any progressive neurological disorder or signs of intracranial pressure.
• Chronic uncontrolled medical conditions that may cause a medical emergency in case of a provoked seizure.
• Metal implants or devices.
• Substance abuse or dependence within the past six months.
• Certain prescription medications that decrease cortical seizure threshold.
• Pregnancy.

Where it is running

• Boston Children's Hospital — Boston, Massachusetts, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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