Magnesium Sulfate in Obese Preeclamptics

Completed · Phase 4

Conditions studied: Preeclampsia

In brief

The purpose of this study is to learn how medications participant will receive in the course of their delivery are metabolized (broken down by the body). The investigators hope to learn more about the way drugs are metabolized by pregnant women, and how those drugs are distributed in the blood and body compartments and cleared in the urine, and how maternal body weight affects the metabolism. With this information the investigators will be able to develop a treatment regimen considering factors in the body that affect magnesium levels so that the investigators can improve treatment of pregnant women. The goal of the study is to understand how different dosing of magnesium sulfate affects blood levels of the magnesium in larger women.

Key facts

Study ID

NCT02835339

Run by

Oregon Health and Science University

People needed

66

Starts

2016-07-12

Expected to finish

2019-06-30

Last updated by the study team

2020-05-13

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Pregnant women who are ages 18-45
• 32-42 weeks' pregnant
• Prescribed magnesium sulfate for preeclampsia
• BMI ≥35 kg/m2

You may not qualify if…

• Pregnant women < 32 weeks' pregnant
• Women who are on dialysis

Where it is running

• Oregon Health & Science Univerity — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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