Impact of Sleep Restriction in Women

Completed · Not applicable

Conditions studied: Sleep, Cardiovascular Disease, Obesity

In brief

The overall goal of this project is to test the hypothesis that long-term, sustained sleep restriction (SR), in women, will lead to increased cardio-metabolic risk. This will be characterized by increases in visceral adiposity, unhealthy lifestyle behaviors (poor dietary quality and low physical activity) and cardio-metabolic risk factors (blood pressure, glucose intolerance) relative to habitual sleep (HS). The investigators expect these changes to be worse in pre- compared to post-menopausal women.

Key facts

Study ID

NCT02835261

Run by

Columbia University

People needed

54

Starts

2016-09-01

Expected to finish

2021-02-25

Last updated by the study team

2025-10-14

Who can join

Age: 20 and older, up to 75. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Age 20-75 years old
• All racial/ethnic groups
• Body mass index 18.5-34.9 kg/m2
• Sleep 7-9 h in bed/night with no daytime nap
• Normal scores on:
• Pittsburgh Quality of Sleep Questionnaire Epworth Sleepiness Scale, Berlin Questionnaire, Sleep Disorders Inventory Questionnaire, Beck Depression Inventory, Composite Scale of Morningness/Eveningness, Three Factor Eating Questionnaire

You may not qualify if…

• Smokers (any cigarettes or ex-smoker <3 years)
• Neurological, medical or psychiatric disorder
• Diabetics
• Regular use of any medication or supplement
• Eating and/or sleep disorders
• Contraindications for MRI scanning
• Travel across time zones within 4 wk
• History of drug and alcohol abuse
• Shift worker (or rotating shift worker)
• Caffeine intake >300 mg/d
• Oral contraceptive use or hormone replacement therapy
• Heavy equipment operators
• Commercial long-distance drivers.

Where it is running

• New York Obesity Nutrition Research Center — New York, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.