Fiber Effects on Glycemic Index

Completed · Not applicable

Conditions studied: Healthy

In brief

Primary outcome measure: Changes in plasma glucose concentration over a 3 hour postprandial visit after administration of polydextrose (12g) compared to 0 mg placebo. Secondary outcome measure: Changes in gastrointestinal tolerance and acute bowel changes in 3 days following treatment administration.

Key facts

Study ID: NCT02831738
Run by: Clinical Nutrition Research Center, Illinois Institute of Technology
People needed: 20
Starts: 2016-07-02
Expected to finish: 2016-10-25
Last updated by the study team: 2021-01-27

Who can join

Age: 20 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

*Subject is male or female aged between 20 and 55 years of age
Subject has BMI between 20.0 and 32.0 kg/m2 at the screening visit
Fasting blood sugar less than 126 mg/dL
Subject is willing to maintain a stable body weight and to follow his/her regular diet and physical activity patterns throughout the study period.
Subject is willing to refrain from vigorous physical activity and consumption of alcoholic and/or caffeinated beverages 24 h prior to each test day
Subject does not smoke or has abstained from smoking for at least 2 years
No clinical evidence of cardiovascular, metabolic, respiratory, renal, gastrointestinal or hepatic disease
Not taking any medications or dietary supplements that would interfere with outcomes of the study.
Subject typically consumes a low fiber diet that correlates with the average fiber intake of typical western diet.

You may not qualify if…

*Subject currently smokes or has smoked within the past 2 years
Men and women with known or suspected food intolerance, allergies or hypersensitivity to the study materials or closely related compounds
Men and women known to have/diagnosed with diabetes mellitus
Men and women with a fasting blood glucose concentration ≥126 mg/dL
Average blood pressure > 140 mmHg/90 mmHg during screening visit
Men and women with documented vascular disease, e.g., heart failure, myocardial infarction, stroke, angina, related surgeries
Men and women with cancer other than non-melanoma skin cancer in previous 5 years
Men and women who are taking medication or dietary supplements that may interfere with the outcomes of the study. Subjects may choose to go off dietary supplements (requires 30 days washout)

Where it is running

Clinical Nutrition Research Center — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.