Randomised Evaluation of Sodium Dialysate Levels on Vascular Events

Recruiting now · Phase 4

Conditions studied: End-Stage Kidney Disease

In brief

This global study will assess the effect of randomising dialysis sites to one of two default dialysate sodium concentrations in current practice, 140mmol/l and 137mmol/l, on major cardiovascular events and death in patients receiving maintenance haemodialysis.

Key facts

Study ID

NCT02823821

Run by

University of Sydney

People needed

50000

Starts

2016-06-01

Expected to finish

2026-12-01

Last updated by the study team

2025-04-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Casey Hospital — Melbourne, Australia (enrolling)
• Cranbourne Integrated Care Centre — Melbourne, Australia (enrolling)
• Nambour General Hospital — Nambour, Australia (enrolling)
• Hampstead Dialysis Centre — Northfield, Australia (enrolling)
• Hervey Bay Hospital — Pialba, Australia (enrolling)
• Royal North Shore Hospital — St Leonards, Australia (enrolling)
• Sunshine Coast University Hospital — Sunshine Coast, Australia (enrolling)
• Sydney Adventist Hospital — Sydney, Australia (enrolling)
• Concord Repatriation and General Hospital — Sydney, Australia (enrolling)
• Blacktown Regional Dialysis Centre — Sydney, Australia (enrolling)
• Mt Druitt Community Dialysis Centre — Sydney, Australia (enrolling)
• Nepean Hospital — Sydney, Australia (enrolling)
• Westmead Hospital — Sydney, Australia (enrolling)
• The Queen Elizabeth Hospital — Woodville South, Australia (enrolling)
• Brantford General Hospital — Brantford, Ontario, Canada (enrolling)
• Chatam-Kent Health Alliance — Chatham, Ontario, Canada (enrolling)
• St Joseph's Healthcare — Hamilton, Ontario, Canada (enrolling)
• Hanover District Hospital — Hanover, Ontario, Canada (enrolling)
• Adam Linton Dialysis Unit - Victoria Hospital — London, Ontario, Canada (enrolling)
• London Health Sciences Centre — London, Ontario, Canada (enrolling)
• Westmount Kidney Care Centre — London, Ontario, Canada (enrolling)
• Grey Bruce Health Services — Owen Sound, Ontario, Canada (enrolling)
• Bluewater Hospital — Sarnia, Ontario, Canada (enrolling)
• Huron Perth Hospital Partnership — Stratford, Ontario, Canada (enrolling)
• Monash Health Community Dandenong — Melbourne, Australia (enrolling)

Full record on ClinicalTrials.gov

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