Spinal Anesthesia in Total Hip Arthroplasty

Stopped early · Phase 4

Conditions studied: Total Hip Arthroplasty

In brief

Spinal anesthesia is commonly used in patients undergoing total hip replacements. The purpose of this study is to compare lidocaine to bupivacaine spinal anesthesia in patients having a total hip arthroplasty (THA). The objective of this study is to compare the two spinal anesthesia treatments in regards to transient neurological symptoms (TNS).

Key facts

Study ID

NCT02818894

Run by

Thomas L Bradbury

People needed

135

Starts

2016-09-27

Expected to finish

2020-03-05

Last updated by the study team

2022-09-23

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Radiographic evidence of symptomatic osteoarthritis in one or bilateral hips. Osteoarthritis will be defined as pain with weight-bearing at the hip articulation together with radiographic findings
• Indicated for total hip arthroplasty
• Agreement to undergo spinal anesthesia for surgery

You may not qualify if…

• Patient refusal to undergo spinal anesthesia
• Patients with a known history of lumbar or sacral spinal fusion.
• Patients with a known history of prostate, urological, or kidney surgery.
• Patients who need monitoring of urine output during surgery (including patients with confirmed renal disease, renal failure, chronic renal insufficiency, or an indwelling catheter at the time of surgery).
• Current infection at site of injection
• Women of child-bearing potential who are on Medicare (child-bearing potential will be determined prior to surgery per Anesthesia standard of care)
• Hypovolemia
• Indeterminate neurologic disease
• Allergy or hypersensitivity to the study medications
• Currently taking any anti-coagulation medications or coagulopathic
• Increased intracranial pressure
• Subject is unable to make his/her own decision regarding the informed consent
• Subject is unable to read/understand English

Where it is running

• Emory University Orthopaedic and Spine Hospital — Atlanta, Georgia, United States
• The Emory Clinic — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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