Remote Ischemic Preconditioning for Carotid Endarterectomy

Completed · Not applicable

Conditions studied: Carotid Stenosis, Endarterectomy, Carotid

In brief

This is a randomized controlled trial designed to test an intervention (Remote ischemic preconditioning) in patients undergoing carotid endarterectomy (CEA) for carotid artery stenosis (CAS). The outcomes of interest include neurocognitive function, cardiac complications, and biomarkers of brain ischemia.

Key facts

Study ID

NCT02808754

Run by

University of Pittsburgh

People needed

86

Starts

2016-12-01

Expected to finish

2019-01-01

Last updated by the study team

2019-02-08

Who can join

Age: 55 and older, up to 95. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients undergoing carotid endarterectomy
• Indication for surgery must be symptomatic disease with >50% stenosis by duplex ultrasound or asymptomatic disease with >60% stenosis by duplex ultrasound

You may not qualify if…

• Lack of radial pulse on either arm
• Known Deep venous thrombosis (DVT) in arm
• Arteriovenous fistula or graft in both arms
• Diagnosed hypercoagulable state
• Pre-existing lymphedema or axillary node dissection both arms
• Diagnosis of dementia, intellectual disability, or mental illness including depression, anxiety, or schizophrenia
• Simultaneous coronary artery bypass grafting

Where it is running

• UPMC — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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